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United States

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製品番号: HY-167671

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BE-10988

BE-10988 is a DNA topoisomerase inhibitor. BE-10988 inhibits the growth of Doxorubicin (HY-15142A)-resistant and vincristine-resistant P388 mouse leukemia cell lines by increasing the formation of DNA topoisomerase complexes.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 135261-89-1
分子式: C₁₃H₁₀N₄O₃S
分子量:302.31

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

BE-10988 構造式

CAS 番号: 135261-89-1

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Topoisomerase アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
SK-BR-3	IC₅₀	8.7 μM Compound: 1	The IC50 value was measured on human breast cancer cell line SK-BR-3. The IC50 value was measured on human breast cancer cell line SK-BR-3.	[PMID: 7699696]
V79	IC₅₀	5.1 μM Compound: 1	The IC50 value was measured on V79 cells in the presence of nitrogen using MTT assay. The IC50 value was measured on V79 cells in the presence of nitrogen using MTT assay.	[PMID: 7699696]
V79	IC₅₀	6.2 μM Compound: 1	The IC50 value was measured on V79 cells in the presence of air using MTT assay. The IC50 value was measured on V79 cells in the presence of air using MTT assay.	[PMID: 7699696]

化学情報

CAS 番号 135261-89-1
分子量 302.31
分子式 C₁₃H₁₀N₄O₃S
SMILES

O=C(C1=CSC(C2=CN(C)C(C(C=C3N)=O)=C2C3=O)=N1)N
Structure Classification
- Quinones
- Benzene Quinones
Initial Source
- Microorganism
Actinomycetes
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Oka H, et al. A NEW TOPOISOMERASE-II INHIBITOR, BE-10988, PRODUCED BY A STREPTOMYCETE I. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION[J]. The Journal of Antibiotics, 1991, 44(5): 486-491. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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