Benzoyleneurea
Based on 1 publication(s) in Google Scholar
Benzoyleneurea possesses anti-bacterial activity. Benzoyleneurea scaffold can be used in the synthesis of novel protein geranylgeranyltransferase-I (PGGTase-I) inhibitors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.66%
- CAS 番号: 86-96-4
- 分子式: C8H6N2O2
- 分子量:162.15
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
MedChemExpress(MCE)の使用を引用している文献 Benzoyleneurea
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生物活性
製品説明
化学情報
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CAS 番号 86-96-4
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性状 Solid
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分子量 162.15
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分子式 C8H6N2O2
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Color White to yellow
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SMILES
O=C(N1)NC2=C(C=CC=C2)C1=O
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別名
quinazolinedione; ベンゾイレン尿素
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Phytomedicine
Tryptanthrin suppresses multiple inflammasome activation to regulate NASH progression by targeting ASC protein. [Abstract]2024 Aug:131:155758. PMID: 38843643
溶剤 & 溶解度
体外:
DMSO : 43.33 mg/mL (267.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
体内:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
純度とドキュメンテーション
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データシート (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.1671 mL | 30.8356 mL | 61.6713 mL | 154.1782 mL |
| 5 mM | 1.2334 mL | 6.1671 mL | 12.3343 mL | 30.8356 mL | |
| 10 mM | 0.6167 mL | 3.0836 mL | 6.1671 mL | 15.4178 mL | |
| 15 mM | 0.4111 mL | 2.0557 mL | 4.1114 mL | 10.2785 mL | |
| 20 mM | 0.3084 mL | 1.5418 mL | 3.0836 mL | 7.7089 mL | |
| 25 mM | 0.2467 mL | 1.2334 mL | 2.4669 mL | 6.1671 mL | |
| 30 mM | 0.2056 mL | 1.0279 mL | 2.0557 mL | 5.1393 mL | |
| 40 mM | 0.1542 mL | 0.7709 mL | 1.5418 mL | 3.8545 mL | |
| 50 mM | 0.1233 mL | 0.6167 mL | 1.2334 mL | 3.0836 mL | |
| 60 mM | 0.1028 mL | 0.5139 mL | 1.0279 mL | 2.5696 mL | |
| 80 mM | 0.0771 mL | 0.3854 mL | 0.7709 mL | 1.9272 mL | |
| 100 mM | 0.0617 mL | 0.3084 mL | 0.6167 mL | 1.5418 mL |