bPiDDB
Based on 1 Customer Validation
bPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.35%
- CAS 番号: 525596-66-1
- 分子式: C24H38Br2N2
- 分子量:514.38
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
bPiDDB is brain bioavailable following peripheral administration and is transported actively by the blood-brain barrier choline transporter into the central compartment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 525596-66-1
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性状 Oil
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分子量 514.38
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分子式 C24H38Br2N2
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Color Off-white to light yellow
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SMILES
CC1=C[N+](CCCCCCCCCCCC[N+]2=CC=CC(C)=C2)=CC=C1.[Br-].[Br-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (194.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
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- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9441 mL | 9.7204 mL | 19.4409 mL | 48.6022 mL |
| 5 mM | 0.3888 mL | 1.9441 mL | 3.8882 mL | 9.7204 mL | |
| 10 mM | 0.1944 mL | 0.9720 mL | 1.9441 mL | 4.8602 mL | |
| 15 mM | 0.1296 mL | 0.6480 mL | 1.2961 mL | 3.2401 mL | |
| 20 mM | 0.0972 mL | 0.4860 mL | 0.9720 mL | 2.4301 mL | |
| 25 mM | 0.0778 mL | 0.3888 mL | 0.7776 mL | 1.9441 mL | |
| 30 mM | 0.0648 mL | 0.3240 mL | 0.6480 mL | 1.6201 mL | |
| 40 mM | 0.0486 mL | 0.2430 mL | 0.4860 mL | 1.2151 mL | |
| 50 mM | 0.0389 mL | 0.1944 mL | 0.3888 mL | 0.9720 mL | |
| 60 mM | 0.0324 mL | 0.1620 mL | 0.3240 mL | 0.8100 mL | |
| 80 mM | 0.0243 mL | 0.1215 mL | 0.2430 mL | 0.6075 mL | |
| 100 mM | 0.0194 mL | 0.0972 mL | 0.1944 mL | 0.4860 mL |
bPiDDB 関連分類
HY-107674 関連分類
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