Chlorophyll b
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Chlorophyll b is an orally active tetrapyrrole derivative and pigment. Chlorophyll b can be obtained from photosynthetic organisms such as plants and algae. Chlorophyll b acts as a hydrogen donor and increases Glutathione levels. Chlorophyll b has antioxidant activity and functionally replaces chlorophyll a in photosystem II to participate in photosynthesis. Chlorophyll b reduces Cisplatin (HY-17394)-induced DNA damage, chromosome instability, and oxidative stress. Chlorophyll b is mainly used in the study of plant photosynthesis mechanism.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.46%
- CAS 番号: 519-62-0
- 分子式: C55H70MgN4O6
- 分子量:907.47
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
体外実験
Chlorophyll b can serve as the major pigment in functional photosystem II complexes of cyanobacteria when introduced into a photosystem I-less strain of Synechocystis sp. PCC 6803 along with lhcb encoding light-harvesting complex (LHC)II from pea[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
Chlorophyll b (0.5 mg/kg; gavage; daily; 13 days) combined with lutein shows antigenotoxic and antimutagenic effects as well as prevents Cisplatin-induced GSH depletion in peripheral blood cells in mice[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female and male albino Swiss mice (Mus musculus) (both genders, approximately 30 g, 7-8 weeks old)[3]
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Dosage:0.5 mg/kg body weight
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Administration:Administered daily by gavage for 13 consecutive days
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Result:Presented antigenotoxic and antimutagenic effects in different cell types of mice, such as peripheral blood, bone marrow, liver, and kidney cells.
Prevented the glutathione depletion induced by cisplatin in peripheral blood cells, maintaining the glutathione concentration at a level similar to the control group.
Had no significant effect on catalase activity.
化学情報
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CAS 番号 519-62-0
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性状 Solid
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分子量 907.47
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分子式 C55H70MgN4O6
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Color Green to dark green
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SMILES
CC1=C2[N-]3[Mg+2]45[N]6=C(C=C7[N-]4C(C(C=C)=C7C)=CC8=[N]5C(C(CC)=C8C=O)=C2)[C@@H](C)[C@H](CCC(OC/C=C(C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=O)C6=C9C3=C1C([C@@H]9C(OC)=O)=O
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別名
Chlorophyll b
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
Ethanol : 10 mg/mL (11.02 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (281 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Xu H, et al. Chlorophyll b can serve as the major pigment in functional photosystem II complexes of cyanobacteria. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):14168-73. [Content Brief]
[2]. Serpeloni JM, et al. An evaluation, using the comet assay and the micronucleus test, of the antigenotoxic effects of chlorophyll b in mice. Mutat Res. 2011 Oct 9;725(1-2):50-6. [Content Brief]
[3]. Serpeloni JM, et al. Effects of lutein and chlorophyll b on GSH depletion and DNA damage induced by cisplatin in vivo. Hum Exp Toxicol. 2013 Aug;32(8):828-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.1020 mL | 5.5098 mL | 11.0196 mL | 27.5491 mL |
| 5 mM | 0.2204 mL | 1.1020 mL | 2.2039 mL | 5.5098 mL | |
| 10 mM | 0.1102 mL | 0.5510 mL | 1.1020 mL | 2.7549 mL |
Chlorophyll b 関連分類
HY-W127709 関連分類
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