Cl-PEG6-acid
Based on 1 Customer Validation
Cl-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 2365309-92-6
- 分子式: C14H27ClO8
- 分子量:358.81
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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PEGs |
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 2365309-92-6
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性状 Liquid (Density: 1.181±0.06 g/cm3)
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分子量 358.81
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分子式 C14H27ClO8
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Color Colorless to light yellow
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SMILES
OC(COCCOCCOCCOCCOCCOCCCl)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (278.70 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7870 mL | 13.9350 mL | 27.8699 mL | 69.6748 mL |
| 5 mM | 0.5574 mL | 2.7870 mL | 5.5740 mL | 13.9350 mL | |
| 10 mM | 0.2787 mL | 1.3935 mL | 2.7870 mL | 6.9675 mL | |
| 15 mM | 0.1858 mL | 0.9290 mL | 1.8580 mL | 4.6450 mL | |
| 20 mM | 0.1393 mL | 0.6967 mL | 1.3935 mL | 3.4837 mL | |
| 25 mM | 0.1115 mL | 0.5574 mL | 1.1148 mL | 2.7870 mL | |
| 30 mM | 0.0929 mL | 0.4645 mL | 0.9290 mL | 2.3225 mL | |
| 40 mM | 0.0697 mL | 0.3484 mL | 0.6967 mL | 1.7419 mL | |
| 50 mM | 0.0557 mL | 0.2787 mL | 0.5574 mL | 1.3935 mL | |
| 60 mM | 0.0464 mL | 0.2322 mL | 0.4645 mL | 1.1612 mL | |
| 80 mM | 0.0348 mL | 0.1742 mL | 0.3484 mL | 0.8709 mL | |
| 100 mM | 0.0279 mL | 0.1393 mL | 0.2787 mL | 0.6967 mL |
Cl-PEG6-acid 関連分類
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