CM-272 (Standard)

CM-272 (Standard) is the analytical standard of CM-272 (HY-101925). This product is intended for research and analytical applications. CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death.

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  • CAS 番号: 1846570-31-7
  • 分子式: C28H38N4O3
  • 分子量:478.63
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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