Coumoxystrobin
Coumoxystrobin is a methoxyacrylate strobilurin fungicide with anti-fungal activity. Coumoxystrobin exhibits inhibitory activity against mycelial growth of Magnaporthe oryzae, increases cell membrane permeability, and reduces respiration. Coumoxystrobin shows protective activity against Magnaporthe oryzae in detached barley leaves. Coumoxystrobin reduces ATP activity of Chlorella vulgaris, thereby causing algal death. Coumoxystrobin can be used in studies related to rice blast disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 850881-70-8
- 分子式: C26H28O6
- 分子量:436.50
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Coumoxystrobin (0.0025-0.08 μg/mL; 7 days) potently inhibits mycelial growth of 100 strains of Magnaporthe oryzae, with a mean EC50 value of 0.0163 μg·mL−1[1].
Coumoxystrobin (0.1 μg/mL; 3 days) exerts teratogenic effects on the mycelial growth of Magnaporthe oryzae strains L-14, L-15 and YE-9, causing mycelial tip distortion and increased apical branching[1].
Coumoxystrobin (0.1 μg/mL; 48 h) disrupts the cell membrane permeability of Magnaporthe oryzae strains L-15 and YE-9, resulting in increased cellular electrolyte leakage[1].
Coumoxystrobin (0.1 μg/mL) significantly reduces the cellular respiration rates of Magnaporthe oryzae strains L-15 and YE-9[1].
Coumoxystrobin (1-4 μg/mL) exhibits dose-dependent protective activity against the YE-9 strain of *Magnaporthe oryzae* on detached barley leaves[1].
Coumoxystrobin (0.5-8 mg/L; 96 h) exhibits acute toxicity to Chlorella vulgaris, with an EC50 of 1.62 mg/L. After 96 h of exposure, the concentration of 4.23 mg/L reduces cell yield by 97.8%[2].
Coumoxystrobin (0.15-1.08 mg/L; 24-96 h) inhibits mitochondrial complex Ⅲ activity and reduces ATP viability in Chlorella vulgaris[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Chlorella vulgaris (FACHB-8)
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Concentration:0.5, 1.0, 2.0, 4.0 and 8.0 mg/L
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Incubation Time:96 h
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Result:Exhibited acute toxicity to Chlorella vulgaris, with an EC50 of 1.62 mg/L, after 96 h of exposure, the concentration of 4.23 mg/L reduces cell yield by 97.8%.
化学情報
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CAS 番号 850881-70-8
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分子量 436.50
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分子式 C26H28O6
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SMILES
CC=1C=2C(=CC(OCC3=C(\C(\C(OC)=O)=C/OC)C=CC=C3)=CC2)OC(=O)C1CCCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Xin W, et al. In vitro fungicidal activity and in planta control efficacy of coumoxystrobin against Magnaporthe oryzae. Pestic Biochem Physiol. 2020;162:78-85. [Content Brief]
[2]. Wang K, et al. Respiratory Toxicity of Azoxystrobin, Pyraclostrobin and Coumoxystrobin on Chlorella vulgaris. Bull Environ Contam Toxicol. 2020;104(6):799-803. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)