CP-312
Based on 1 Customer Validation
CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.18%
- CAS 番号: 895470-67-4
- 分子式: C16H12ClN3OS2
- 分子量:361.87
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
体外実験
CP-312 (10 µM; 2 h) exhibits good potency in protecting hiPSC-CMs from acute peroxide-induced cell death with EC50 = 6.7 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 895470-67-4
-
性状 Solid
-
分子量 361.87
-
分子式 C16H12ClN3OS2
-
Color Off-white to pink
-
SMILES
O=C(NC1=NC(C2=NC=CC=C2)=CS1)CSC3=CC=C(Cl)C=C3
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (276.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (270 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7634 mL | 13.8171 mL | 27.6342 mL | 69.0856 mL |
| 5 mM | 0.5527 mL | 2.7634 mL | 5.5268 mL | 13.8171 mL | |
| 10 mM | 0.2763 mL | 1.3817 mL | 2.7634 mL | 6.9086 mL | |
| 15 mM | 0.1842 mL | 0.9211 mL | 1.8423 mL | 4.6057 mL | |
| 20 mM | 0.1382 mL | 0.6909 mL | 1.3817 mL | 3.4543 mL | |
| 25 mM | 0.1105 mL | 0.5527 mL | 1.1054 mL | 2.7634 mL | |
| 30 mM | 0.0921 mL | 0.4606 mL | 0.9211 mL | 2.3029 mL | |
| 40 mM | 0.0691 mL | 0.3454 mL | 0.6909 mL | 1.7271 mL | |
| 50 mM | 0.0553 mL | 0.2763 mL | 0.5527 mL | 1.3817 mL | |
| 60 mM | 0.0461 mL | 0.2303 mL | 0.4606 mL | 1.1514 mL | |
| 80 mM | 0.0345 mL | 0.1727 mL | 0.3454 mL | 0.8636 mL | |
| 100 mM | 0.0276 mL | 0.1382 mL | 0.2763 mL | 0.6909 mL |