CP-424174
Based on 1 Customer Validation
CP-424174 is a reversible inhibitor against IL-1β processing with an IC50 of 210 nM.CP-424174 indirectly inhibits NLRP3.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.69%
- CAS 番号: 210825-31-3
- 分子式: C22H29ClN2O4S
- 分子量:452.99
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
化学情報
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CAS 番号 210825-31-3
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性状 Solid
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分子量 452.99
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分子式 C22H29ClN2O4S
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Color White to off-white
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SMILES
O=S(C1=CC=CC(C(O)(C)C)=C1)(NC(NC2=C(C=C(C=C2C(C)C)Cl)C(C)C)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (275.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2076 mL | 11.0378 mL | 22.0755 mL | 55.1889 mL |
| 5 mM | 0.4415 mL | 2.2076 mL | 4.4151 mL | 11.0378 mL | |
| 10 mM | 0.2208 mL | 1.1038 mL | 2.2076 mL | 5.5189 mL | |
| 15 mM | 0.1472 mL | 0.7359 mL | 1.4717 mL | 3.6793 mL | |
| 20 mM | 0.1104 mL | 0.5519 mL | 1.1038 mL | 2.7594 mL | |
| 25 mM | 0.0883 mL | 0.4415 mL | 0.8830 mL | 2.2076 mL | |
| 30 mM | 0.0736 mL | 0.3679 mL | 0.7359 mL | 1.8396 mL | |
| 40 mM | 0.0552 mL | 0.2759 mL | 0.5519 mL | 1.3797 mL | |
| 50 mM | 0.0442 mL | 0.2208 mL | 0.4415 mL | 1.1038 mL | |
| 60 mM | 0.0368 mL | 0.1840 mL | 0.3679 mL | 0.9198 mL | |
| 80 mM | 0.0276 mL | 0.1380 mL | 0.2759 mL | 0.6899 mL | |
| 100 mM | 0.0221 mL | 0.1104 mL | 0.2208 mL | 0.5519 mL |