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United States

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製品番号: HY-N18312

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Crepidatin

Crepidatin is a bibenzyl compound that can be isolated from the stems of Dendrobium loddigesii. Crepidatin promotes anoikis of lung cancer cells. Crepidatin inhibits the anchorage-independent growth of human lung cancer cells. Crepidatin can be used in lung cancer-related research.

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CAS 番号: 101508-50-3
分子式: C₁₈H₂₂O₅
分子量:318.36

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Crepidatin 構造式

CAS 番号: 101508-50-3

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
NCI-H23	IC₅₀	157.77 μM Compound: 12	Anti-cancer activity against human NCI-H23 cells Anti-cancer activity against human NCI-H23 cells	[PMID: 32711292]

体外実験

Crepidatin (Compound 3) exhibits cytotoxic activity against H23 cells after 24 h, with an IC₅₀ value of 157.77 μM^[1].
Crepidatin (0-1 μM; 24 h) significantly enhances anoikis in H23 cells^[1].
Crepidatin (0-1 μM; 4 weeks) significantly inhibits the anchorage-independent growth of H23 cells by reducing colony number and diameter^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:

H23 cells
Concentration:

0, 0.5, 1 μM
Incubation Time:

4 weeks (suspended soft agar culture)
Result:

Significantly reduced relative colony numbe and relative colony diamete compared to untreated control.
Further reduced relative colony number nd relative colony diameter compared to untreated control at 1 μM.

Apoptosis Analysis^[1]

Cell Line:

H23 cells
Concentration:

0, 0.5, 1 μM
Incubation Time:

24 h
Result:

Caused significant enhancing effect on cell anoikis in a concentration-dependent manner.

化学情報

CAS 番号 101508-50-3
分子量 318.36
分子式 C₁₈H₂₂O₅
SMILES

OC1=CC=C(CCC2=CC(OC)=C(C(OC)=C2)OC)C=C1OC
Structure Classification
- Phenols
- Monophenols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Chanvorachote P, et al. Anti-metastatic activities of bibenzyls from Dendrobium pulchellum. Nat Prod Commun. 2013;8(1):115-118. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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