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製品番号: HY-D3284

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CSF1

CSF1 is a silicon-rhodamine-based, fluorescence-activatable probe with selectivity for Cu⁺. CSF1 colocalizes with the endoplasmic reticulum in live cells.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 2158211-22-2
分子式: C₃₉H₅₁F₃N₂O₂S₄Si
分子量:793.18

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

CSF1 構造式

CAS 番号: 2158211-22-2

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

CSF1 is a silicon-rhodamine-based, fluorescence-activatable probe with selectivity for Cu⁺. CSF1 colocalizes with the endoplasmic reticulum in live cells^[1].

体外実験

CSF1 serves as a fluorescent sensor for the specific recognition of Cu⁺ in aqueous buffer systems, with a K_d value of 0.49 pM, and its fluorescence response increases 17-fold upon binding to Cu⁺^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

臨床実験

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

化学情報

CAS 番号 2158211-22-2
分子量 793.18
分子式 C₃₉H₅₁F₃N₂O₂S₄Si
SMILES

CCSCCSCCN(CC1=CC=C(C(C(F)(F)F)=C1)C2=C3C=CC(C=C3[Si](C)(C4=C2C=CC(N5CCOCC5)=C4)C)=O)CCSCCSCC
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Jia S, et al. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2018;13(7):1844-1852. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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