DBCO-PEG10-DBCO
Based on 1 Customer Validation
DBCO-PEG10-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG10-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 96.97%
- 分子式: C60H74N4O14
- 分子量:1075.25
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Oil
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分子量 1075.25
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分子式 C60H74N4O14
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Color Light yellow to yellow
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SMILES
O=C(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NCCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (93.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9300 mL | 4.6501 mL | 9.3002 mL | 23.2504 mL |
| 5 mM | 0.1860 mL | 0.9300 mL | 1.8600 mL | 4.6501 mL | |
| 10 mM | 0.0930 mL | 0.4650 mL | 0.9300 mL | 2.3250 mL | |
| 15 mM | 0.0620 mL | 0.3100 mL | 0.6200 mL | 1.5500 mL | |
| 20 mM | 0.0465 mL | 0.2325 mL | 0.4650 mL | 1.1625 mL | |
| 25 mM | 0.0372 mL | 0.1860 mL | 0.3720 mL | 0.9300 mL | |
| 30 mM | 0.0310 mL | 0.1550 mL | 0.3100 mL | 0.7750 mL | |
| 40 mM | 0.0233 mL | 0.1163 mL | 0.2325 mL | 0.5813 mL | |
| 50 mM | 0.0186 mL | 0.0930 mL | 0.1860 mL | 0.4650 mL | |
| 60 mM | 0.0155 mL | 0.0775 mL | 0.1550 mL | 0.3875 mL | |
| 80 mM | 0.0116 mL | 0.0581 mL | 0.1163 mL | 0.2906 mL |
DBCO-PEG10-DBCO 関連分類
HY-140304 関連分類
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