3,3'-ジチオジプロピオン酸
Based on 1 Customer Validation
Dithiodipropionic acid can interact with CPUL1 (HY-151802) (a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.0%
- CAS 番号: 1119-62-6
- 分子式: C6H10O4S2
- 分子量:210.26
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
CPUL1-DA NAs (molar ratio was 1:2) inhibits HUH7 hepatoma cell viability with an IC50 value of 4.3 μM, and has weak cytotoxicity against normal L02 cells[1].
CPUL1-DA NAs (2.5-10 μM, 6 h) can be more effectively enriched in HUH7 cells mitochondria and displays faster cellular uptake ability to deliver CPUL1 into cells than that of free CPUL1[1].
CPUL1-DA NAs (2.5-10 μM, 12 h) results in the accumulation of superoxides and mitochondrial membrane damage in HUH7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 1119-62-6
-
性状 Solid
-
分子量 210.26
-
分子式 C6H10O4S2
-
Color White to off-white
-
SMILES
O=C(O)CCSSCCC(O)=O
-
別名
2-カルボキシエチルジスルフィド; β,β-チオジプロピオン酸; Dithiodipropionic acid; Propanoic acid, 3,3'-dithiobis-; 3,3-Dithiodipropionic acid; 2-Carboxyethyl disulfide
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (475.60 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (267 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7560 mL | 23.7801 mL | 47.5602 mL | 118.9004 mL |
| 5 mM | 0.9512 mL | 4.7560 mL | 9.5120 mL | 23.7801 mL | |
| 10 mM | 0.4756 mL | 2.3780 mL | 4.7560 mL | 11.8900 mL | |
| 15 mM | 0.3171 mL | 1.5853 mL | 3.1707 mL | 7.9267 mL | |
| 20 mM | 0.2378 mL | 1.1890 mL | 2.3780 mL | 5.9450 mL | |
| 25 mM | 0.1902 mL | 0.9512 mL | 1.9024 mL | 4.7560 mL | |
| 30 mM | 0.1585 mL | 0.7927 mL | 1.5853 mL | 3.9633 mL | |
| 40 mM | 0.1189 mL | 0.5945 mL | 1.1890 mL | 2.9725 mL | |
| 50 mM | 0.0951 mL | 0.4756 mL | 0.9512 mL | 2.3780 mL | |
| 60 mM | 0.0793 mL | 0.3963 mL | 0.7927 mL | 1.9817 mL | |
| 80 mM | 0.0595 mL | 0.2973 mL | 0.5945 mL | 1.4863 mL | |
| 100 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 1.1890 mL |
Dithiodipropionic acid 関連分類
HY-W014395 関連分類
Powered by Bioz