DOPE-mPEG500
DOPE-mPEG500 is a PEGylated phospholipid containing DOPE. DOPE-mPEG500 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
生物活性
The structure of DOPE-mPEG comprises two key components that work synergistically:
DOPE: Containing two oleoyl groups (C18:1), it imparts excellent membrane fluidity and promotes membrane fusion under acidic conditions (such as endosome escape).
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COP(OCCNC(OCCOC)=O)(O)=O)=O.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DOPE-mPEG500 関連分類
HY-W440988B 関連分類
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