E-2101
E-2101 is a novel antispastic agent. E-2101 is a competitive CYP2C19 and CYP2D6 inhibitor with Ki values of 15 and 48 μM, respectively. E-2101 is metabolized by Cytochromes P450 to form monohydroxylated (M1 and M2), dihydroxylated (M3), and N-dealkylated metabolites (M4). E-2101 can be used in the research of skeletal muscle spasm.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 265667-22-9
- 分子式: C24H28FN3O
- 分子量:393.50
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
CYP2C19 15 μM (Ki) |
CYP2D6 48 μM (Ki) |
化学情報
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CAS 番号 265667-22-9
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分子量 393.50
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分子式 C24H28FN3O
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SMILES
O=C(NC)CC1=CC2=C(C=C1)C=CN2C3CCN(CCC4=CC=CC=C4F)CC3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Zhang ZY, et al. In vitro interactions between a potential muscle relaxant E2101 and human cytochromes P450. Drug Metab Dispos. 2002 Jul;30(7):805-13. [Content Brief]
[2]. Kushida, et al. Solid state characterization of E2101, a novel antispastic drug. J Pharm Sci. 2002 Oct;91(10):2193-202. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
E-2101 関連分類
HY-19379 関連分類
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