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製品番号: HY-18600B

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(E)-Azimilide

Name: (E)-Azimilide
Brand: MedChemExpress
SKU: HY-18600B
Availability: PreOrder

(別名: (E)-NE-10064)

(E)-Azimilide is an isomer of Azimilide (HY-18600), a class of antiarrhythmic compounds that inhibit I(Ks) and I(Kr) activity.

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CAS 番号: 1294552-65-0
分子式: C₂₃H₂₈ClN₅O₃
分子量:457.95

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

(E)-Azimilide 構造式

CAS 番号: 1294552-65-0

容量

価格（税別）

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数量

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

(E)-Azimilide is an isomer of Azimilide (HY-18600), a class of antiarrhythmic compounds that inhibit I(Ks) and I(Kr) activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Ventricular myocyte	IC₅₀	0.18 μM Compound: 2	Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp technique Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp technique	[PMID: 19185489]
Ventricular myocyte	IC₅₀	0.24 μM Compound: 2	Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-clamp technique Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-clamp technique	[PMID: 19185489]

化学情報

CAS 番号 1294552-65-0
分子量 457.95
分子式 C₂₃H₂₈ClN₅O₃
SMILES

O=C(N(C(C1)=O)CCCCN2CCN(CC2)C)N1/N=C/C3=CC=C(C4=CC=C(C=C4)Cl)O3
別名

(E)-NE-10064
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (263 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Optimization method for assessing cardiac safety risk with high-throughput hERG. China, CN109856349 A 2019-06-07.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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