EDTA-OH
Based on 1 Customer Validation
EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils. EDTA-OH is able to cross brain-blood barrier.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.48%
- CAS 番号: 150-39-0
- 分子式: C10H18N2O7
- 分子量:278.26
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Aluminium overload in wistar rats[3]
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Dosage:50 mg/kg
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Administration:i.p. for 5 days
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Result:Inhibited GST activity, reduced the concentration of aluminium in blood and brain.
化学情報
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CAS 番号 150-39-0
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性状 Solid
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分子量 278.26
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分子式 C10H18N2O7
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Color White to off-white
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SMILES
O=C(O)CN(CCO)CCN(CC(O)=O)CC(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 17.5 mg/mL (62.89 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Li X, Zhang Z, et al., Complexation of Light Trivalent Lanthanides with N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic Acid in Aqueous Solutions: Thermodynamic Analysis and Coordination Modes. Inorg Chem. 2019 Nov 18;58(22):15618-15628. [Content Brief]
[2]. Chen H, et al., EDTA and HEDTA effects on Cd, Cr, and Ni uptake by Helianthus annuus. Chemosphere. 2001 Oct;45(1):21-8. [Content Brief]
[3]. Flora SJ, et al., Aluminum-induced oxidative stress in rat brain: response to combined administration of citric acid and HEDTA. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Mar;134(3):319-28. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.5938 mL | 17.9688 mL | 35.9376 mL | 89.8440 mL |
| 5 mM | 0.7188 mL | 3.5938 mL | 7.1875 mL | 17.9688 mL | |
| 10 mM | 0.3594 mL | 1.7969 mL | 3.5938 mL | 8.9844 mL | |
| 15 mM | 0.2396 mL | 1.1979 mL | 2.3958 mL | 5.9896 mL | |
| 20 mM | 0.1797 mL | 0.8984 mL | 1.7969 mL | 4.4922 mL | |
| 25 mM | 0.1438 mL | 0.7188 mL | 1.4375 mL | 3.5938 mL | |
| 30 mM | 0.1198 mL | 0.5990 mL | 1.1979 mL | 2.9948 mL | |
| 40 mM | 0.0898 mL | 0.4492 mL | 0.8984 mL | 2.2461 mL | |
| 50 mM | 0.0719 mL | 0.3594 mL | 0.7188 mL | 1.7969 mL | |
| 60 mM | 0.0599 mL | 0.2995 mL | 0.5990 mL | 1.4974 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.