EP055
EP055 is a non-hormonal male contraceptive. EP055 targets to sperm protein EPPIN and inhibits anti-EPPIN antibodies from binding EPPIN with an IC50 of 1121 μM. EP055 can inhibit sperm motility (IC50 = 199.5 μM) by reducing the internal pH and Ca2+ levels of the sperm, thereby causing the sperm to aggregate. EP055 can be used for development of male contraceptive.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2411173-40-3
- 分子式: C15H17N7O6S
- 分子量:423.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Spermatozoa | IC50 |
200 μM
Compound: EP055
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Inhibition of sperm motility in human Spermatozoa incubated for 1 to 2 hrs by computer assisted sperm analysis
Inhibition of sperm motility in human Spermatozoa incubated for 1 to 2 hrs by computer assisted sperm analysis
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[PMID: 36087385] |
化学情報
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CAS 番号 2411173-40-3
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分子量 423.40
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分子式 C15H17N7O6S
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SMILES
O=C(CSC1=NC(NC2=CC=C(C(O)=C2)NC(C)=O)=NC(NNC(OC)=O)=N1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
EP055 関連分類
HY-171129 関連分類
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