Epirizole
Based on 1 Customer Validation
Epirizole (Mepirizole) is an orally active NSAID (nonsteroidal anti-inflammatory agent). Epirizole shows anti-inflammatory activity, and can be used in chronic rheumatoid arthritis research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.9%
- CAS 番号: 18694-40-1
- 分子式: C11H14N4O2
- 分子量:234.26
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
体外実験
Epirizole (1-1000 μM; 24 h) increases MDR1 mRNA expression in Caco-2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Caco-2 cells
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Concentration:1, 10, 100, and 1000 μM
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Incubation Time:24 hours
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Result:Increased the level of MDR1 mRNA expression.
化学情報
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CAS 番号 18694-40-1
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性状 Solid
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分子量 234.26
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分子式 C11H14N4O2
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Color White to off-white
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SMILES
CC1=CC(OC)=NC(N2N=C(C)C=C2OC)=N1
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別名
Mepirizole; メピリゾール; DA-398
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
DMSO : 250 mg/mL (1067.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2688 mL | 21.3438 mL | 42.6876 mL | 106.7190 mL |
| 5 mM | 0.8538 mL | 4.2688 mL | 8.5375 mL | 21.3438 mL | |
| 10 mM | 0.4269 mL | 2.1344 mL | 4.2688 mL | 10.6719 mL | |
| 15 mM | 0.2846 mL | 1.4229 mL | 2.8458 mL | 7.1146 mL | |
| 20 mM | 0.2134 mL | 1.0672 mL | 2.1344 mL | 5.3360 mL | |
| 25 mM | 0.1708 mL | 0.8538 mL | 1.7075 mL | 4.2688 mL | |
| 30 mM | 0.1423 mL | 0.7115 mL | 1.4229 mL | 3.5573 mL | |
| 40 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6680 mL | |
| 50 mM | 0.0854 mL | 0.4269 mL | 0.8538 mL | 2.1344 mL | |
| 60 mM | 0.0711 mL | 0.3557 mL | 0.7115 mL | 1.7787 mL | |
| 80 mM | 0.0534 mL | 0.2668 mL | 0.5336 mL | 1.3340 mL | |
| 100 mM | 0.0427 mL | 0.2134 mL | 0.4269 mL | 1.0672 mL |