製品番号: HY-N3845

Ergosterol peroxide

1 Cited Publications

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Ergosterol peroxide is a steroid derivative and can be isolated from a variety of fungi, yeast, lichens or sponges. Ergosterol peroxide has anti-tumour, proapoptotic, anti-inflammatory, anti-mycobacterial, and anti-proliferative activities.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 99.57%
CAS 番号: 2061-64-5
分子式: C₂₈H₄₄O₃
分子量:428.65

保管条件:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Ergosterol peroxide 構造式

CAS 番号: 2061-64-5

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	14.32 μg/mL Compound: 5	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 23511021]
B16	IC₅₀	77.9 μM Compound: 6	Cytotoxicity against murine B16 cells by MTT assay Cytotoxicity against murine B16 cells by MTT assay	[PMID: 17256903]
BV-2	IC₅₀	6.3 μM Compound: 22	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced iNOS-dependent nitrite production after 24 hrs by Griess method Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced iNOS-dependent nitrite production after 24 hrs by Griess method	[PMID: 21028898]
HEK293	EC₅₀	0.85 μM Compound: 2	Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay	[PMID: 22014750]
HeLa	IC₅₀	19.54 μM Compound: Ergosterol peroxide	Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay	[PMID: 38107170]
Hep 3B2	IC₅₀	16.51 μg/mL Compound: 5	Cytotoxicity against human Hep3B cells Cytotoxicity against human Hep3B cells	[PMID: 23511021]
HepG2	IC₅₀	15.27 μg/mL Compound: 5	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 23511021]
HepG2	IC₅₀	23.35 μM Compound: Ergosterol peroxide	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38107170]
KB	ED₅₀	9.79 μg/mL Compound: 4	Cytotoxicity against human KB cells after 4 days Cytotoxicity against human KB cells after 4 days	[PMID: 1791484]
MCF7	IC₅₀	13.41 μg/mL Compound: 5	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 23511021]
MCF7	IC₅₀	18 μM Compound: Ergosterol peroxide	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by CCK8 assay	[PMID: 38107170]
MDA-MB-231	IC₅₀	16.74 μg/mL Compound: 5	Cytotoxicity against human MDA-MB-231 cells Cytotoxicity against human MDA-MB-231 cells	[PMID: 23511021]
PLC-PRF-5	ED₅₀	10.99 μg/mL Compound: 4	Cytotoxicity against human PLC/PRF/5 cells after 4 days Cytotoxicity against human PLC/PRF/5 cells after 4 days	[PMID: 1791484]
RAW264.7	IC₅₀	28.7 μM Compound: 117	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production	[PMID: 31255927]
RAW264.7	IC₅₀	9.4 μM Compound: 9	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method	[PMID: 23357630]
SNU1	IC₅₀	18.7 μM Compound: 231	Cytotoxicity against human SNU1 cells Cytotoxicity against human SNU1 cells	[PMID: 17618015]
SNU-354	IC₅₀	158.2 μM Compound: 231	Cytotoxicity against human SNU354 cells Cytotoxicity against human SNU354 cells	[PMID: 17618015]
SNU-C4	IC₅₀	84.6 μM Compound: 231	Cytotoxicity against human SNUC4 cells Cytotoxicity against human SNUC4 cells	[PMID: 17618015]

化学情報

CAS 番号 2061-64-5
性状 Solid
分子量 428.65
分子式 C₂₈H₄₄O₃
Color White to off-white
SMILES

C[C@@]12[C@]3([H])[C@]4(C=C[C@]1(C[C@H](CC2)O)OO4)[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)/C=C/[C@H](C)C(C)C)C
Structure Classification
- Others
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Publications (1)

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Journal Impact Factor

Lett Drug Des Discov

2026 Feb 11.

溶剤 & 溶解度

体外:

DMSO : 11.11 mg/mL (25.92 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.3329 mL

11.6645 mL

23.3291 mL

5 mM

0.4666 mL

2.3329 mL

4.6658 mL

10 mM

0.2333 mL

1.1665 mL

2.3329 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (272 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Ming Bu, et al. Synthesis of Ergosterol Peroxide Conjugates as Mitochondria Targeting Probes for Enhanced Anticancer Activity. Molecules. 2019 Sep 11;24(18):3307 [Content Brief]

[2]. Taotao Ling, et al. Development of ergosterol peroxide probes for cellular localisation studies. Org Biomol Chem. 2019 May 29;17(21):5223-5229. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.3329 mL	11.6645 mL	23.3291 mL	58.3226 mL
	5 mM	0.4666 mL	2.3329 mL	4.6658 mL	11.6645 mL
	10 mM	0.2333 mL	1.1665 mL	2.3329 mL	5.8323 mL
	15 mM	0.1555 mL	0.7776 mL	1.5553 mL	3.8882 mL
	20 mM	0.1166 mL	0.5832 mL	1.1665 mL	2.9161 mL
	25 mM	0.0933 mL	0.4666 mL	0.9332 mL	2.3329 mL

Keywords

Ergosterol peroxide

1 Cited Publications

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Ergosterol peroxide

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MedChemExpress（MCE）の使用を引用している文献 Ergosterol peroxide

生物活性

化学情報

Publications (1)

溶剤 & 溶解度

純度とドキュメンテーション