EVs inducer-1
EVs inducer-1 is a release inducer of immunostimulatory extracellular vesicles (EVs). EVs inducer-1 inhibits tubulin polymerization. EVs inducer-1 enhances the release of immunostimulatory EVs by antigen-presenting cells, increases the release of EV particles from dendritic cells, and elevates CD63 reporter gene activity. EVs inducer-1 inhibits the viability of proliferating cells. EVs inducer-1 is applicable for research related to immune regulation.
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- CAS 番号: 710280-48-1
- 分子式: C21H13N3OS
- 分子量:355.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
EVs inducer-1 (Compound 1) (10 μM; 48 h) significantly enhances CD63-mediated EV release in human CD63 Tluc-CD9 EmGFP THP-1 reporter cells[1].
EVs inducer-1 (10 μM; 20 h) exhibits extremely low cytotoxicity in primary mBMDC and hPBMC, but inhibits the viability of Jurkat, Ramos, RAW264.7, NIH3T3 and C2C12 cells[1].
EVs inducer-1 (0-10 μM) dose-dependently inhibits tubulin polymerization in cell-free biochemical assays[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Jurkat, Ramos, RAW264.7, NIH3T3, C2C12 cells
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Concentration:10 μM
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Incubation Time:20 h
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Result:Reduced the cells activity (10-70%).
化学情報
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CAS 番号 710280-48-1
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分子量 355.41
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分子式 C21H13N3OS
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SMILES
C1(C=CC=C2)=C2C=CC=C1C3=NN=C(C4=CC(C5=CC=CS5)=CN=C4)O3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
EVs inducer-1 関連分類
HY-182080 関連分類
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