FC9402
Based on 2 publication(s) in Google Scholar
FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.19%
- CAS 番号: 2452401-65-7
- 分子式: C19H16N4O
- 分子量:316.36
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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MedChemExpress（MCE）の使用を引用している文献 FC9402
More
生物活性
SQOR[1]
FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2452401-65-7
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性状 Solid
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分子量 316.36
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分子式 C19H16N4O
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Color Light yellow to yellow
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SMILES
N#CC1=C(OC)N=C(C2=NC=CC=C2C)C=C1C3=CC=C(N)C=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Redox Biol
Knockout of the sulfide: quinone oxidoreductase SQR reduces growth of HCT116 tumor xenograft. [Abstract]2025 Apr 24:83:103650. PMID: 40305883 -
iScience
mCAUSE: Prioritizing mitochondrial targets that alleviate pancreatic cancer cell phenotypes. [Abstract]2024 Sep 3;27(9):110880. PMID: 39310760
溶剤 & 溶解度
DMSO : 100 mg/mL (316.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. WO 2020/146636 A1
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1610 mL | 15.8048 mL | 31.6096 mL | 79.0239 mL |
| 5 mM | 0.6322 mL | 3.1610 mL | 6.3219 mL | 15.8048 mL | |
| 10 mM | 0.3161 mL | 1.5805 mL | 3.1610 mL | 7.9024 mL | |
| 15 mM | 0.2107 mL | 1.0537 mL | 2.1073 mL | 5.2683 mL | |
| 20 mM | 0.1580 mL | 0.7902 mL | 1.5805 mL | 3.9512 mL | |
| 25 mM | 0.1264 mL | 0.6322 mL | 1.2644 mL | 3.1610 mL | |
| 30 mM | 0.1054 mL | 0.5268 mL | 1.0537 mL | 2.6341 mL | |
| 40 mM | 0.0790 mL | 0.3951 mL | 0.7902 mL | 1.9756 mL | |
| 50 mM | 0.0632 mL | 0.3161 mL | 0.6322 mL | 1.5805 mL | |
| 60 mM | 0.0527 mL | 0.2634 mL | 0.5268 mL | 1.3171 mL | |
| 80 mM | 0.0395 mL | 0.1976 mL | 0.3951 mL | 0.9878 mL | |
| 100 mM | 0.0316 mL | 0.1580 mL | 0.3161 mL | 0.7902 mL |
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