Fluoxastrobin
Fluoxastrobin is a fungicide. By binding to NAD-dependent epimerase/dehydratase, Fluoxastrobin interferes with electron transport, reduces ATP production and inhibits mycelial growth, thereby effectively controlling foliar diseases of tea plants. Fluoxastrobin induces oxidative stress by increasing ROS levels and lipid peroxidation, causes DNA damage and promotes apoptosis; meanwhile, it shows high acute toxicity to Danio rerio embryos and larvae. Fluoxastrobin can be used in research related to tea foliar diseases (including tea red leaf spot and tea gray leaf spot).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 361377-29-9
- 分子式: C21H16ClFN4O5
- 分子量:458.83
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
Fluoxastrobin (13.64 μg/mL) inhibits Pestalotiopsis trachicarpicola hyphal growth with an in vitro half-maximal effective concentration of 13.64 μg/mL, disrupts fungal energy metabolism via dose-dependent inhibition of ATP production and elevation of hyphal membrane potential, and binds stably to the fungal NAD-dependent epimerase/dehydratase[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- Detection of Apoptosis
- TUNEL staining for apoptotic DNA fragmentation
- Annexin V plus membrane-impermeant dye apoptosis staining
- ROS/oxidative-stress fluorescent staining
- Apoptosis Solutions
- Filamentous Fungal Mold Culture and Sporulation
- Ferroptosis Solutions
- Genotoxicity/Mutagenicity Study
- Acute Systemic Toxicity Study
化学情報
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CAS 番号 361377-29-9
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分子量 458.83
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分子式 C21H16ClFN4O5
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SMILES
C(=N\OC)(\C1=C(OC=2C(F)=C(OC3=C(Cl)C=CC=C3)N=CN2)C=CC=C1)/C4=NOCCO4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- Fluoxastrobin
- 361377-29-9
- Fungal
- Reactive Oxygen Species (ROS)
- DNA/RNA Synthesis
- Apoptosis
- *Pestalotiopsis trachicarpicola*
- superoxide dismutase
- gray blight
- phytopathogenic fungi
- glutathione peroxidase
- tea leaf spot
- *Danio rerio*
- tea foliar disease pathogens
- NAD-dependent epimerase/dehydratase
- catalase
- Inhibitor
- inhibitor
- inhibit