Flurpiridaz
Based on 1 Customer Validation
Flurpiridaz is a positron emission tomography (PET) myocardial perfusion imaging tracer. Flurpiridaz can bind to mitochondrial complex I with high affinity. Flurpiridaz demonstrates high heart uptake in multiple species with clear delineation of perfusion deficits. Flurpiridaz shows rapid uptake in the myocardium. Flurpiridaz can be studied in research on coronary artery disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.73%
- CAS 番号: 863888-33-9
- 分子式: C18H22ClFN2O3
- 分子量:368.83
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 863888-33-9
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性状 Solid
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分子量 368.83
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分子式 C18H22ClFN2O3
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Color White to off-white
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SMILES
O=C1C(Cl)=C(OCC2=CC=C(C=C2)COCCF)C=NN1C(C)(C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (67.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Maddahi J, et al., Phase-III Clinical Trial of Fluorine-18 Flurpiridaz Positron Emission Tomography for Evaluation of Coronary Artery Disease. J Am Coll Cardiol. 2020 Jul 28;76(4):391-401. [Content Brief]
[2]. Yu M, et al., The next generation of cardiac positron emission tomography imaging agents: discovery of flurpiridaz F-18 for detection of coronary disease. Semin Nucl Med. 2011 Jul;41(4):305-13. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7113 mL | 13.5564 mL | 27.1128 mL | 67.7819 mL |
| 5 mM | 0.5423 mL | 2.7113 mL | 5.4226 mL | 13.5564 mL | |
| 10 mM | 0.2711 mL | 1.3556 mL | 2.7113 mL | 6.7782 mL | |
| 15 mM | 0.1808 mL | 0.9038 mL | 1.8075 mL | 4.5188 mL | |
| 20 mM | 0.1356 mL | 0.6778 mL | 1.3556 mL | 3.3891 mL | |
| 25 mM | 0.1085 mL | 0.5423 mL | 1.0845 mL | 2.7113 mL | |
| 30 mM | 0.0904 mL | 0.4519 mL | 0.9038 mL | 2.2594 mL | |
| 40 mM | 0.0678 mL | 0.3389 mL | 0.6778 mL | 1.6945 mL | |
| 50 mM | 0.0542 mL | 0.2711 mL | 0.5423 mL | 1.3556 mL | |
| 60 mM | 0.0452 mL | 0.2259 mL | 0.4519 mL | 1.1297 mL |
Flurpiridaz 関連分類
HY-180344 関連分類
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