FTEAA
FTEAA is a 4-styrylpiperidine inhibitor. FTEAA exhibits potent inhibitory effect towards both monoamine oxidase with IC50s of 0.52 μM (MAO-A), 1.02 μM (MAO-B), respectively. MAO inhibitors can be used for cardiovascular, neurological and oncological disorders research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C34H26F8N2O2
- 分子量:646.57
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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MAO-A 0.52 μM (IC50) |
MAO-B 1.02 μM (IC50) |
MAO-A and MAO-B act function to lower central nervous system (CNS) concentration of monoamines, regulate the amount and activity of available monoamines[1].
If dopamine levels are too high, MAO levels will increase to compensate. If serotonin levels are too low, then MAO activity will decrease to leave adequate serotonin supplies for the CNS to function optimally[1].
FTEAA inhibits MAO-A and MAO-B with micromolar scale IC50s of 0.52 and 1.02 μM, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Predicted Pharmacokinetic Analysis of FTEAA[2]
| Intestinal Absorption (%) | Total Clearance (log/mL/min/kg) | Max. Tolerable Dose(log mg/kg/day) | RO5 Rulea |
| 95.664 | 0.812 | 0.493 | yes |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 646.57
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分子式 C34H26F8N2O2
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SMILES
O=C(C1=C(NC2=CC=C(F)C=C2)CC(C3=CC=C(C(F)(F)F)C=C3)N(C4=CC=C(F)C=C4)C1C5=CC=C(C(F)(F)F)C=C5)OCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
FTEAA 関連分類
HY-151094 関連分類
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