Furylfuramide
Furylfuramide is a food preservative that exhibits mutagenic activity. Furylfuramide can be degraded through the aerobic metabolism by liver microsomes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3688-53-7
- 分子式: C11H8N2O5
- 分子量:248.19
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
化学情報
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CAS 番号 3688-53-7
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性状 Solid
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分子量 248.19
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分子式 C11H8N2O5
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Color Orange to red
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SMILES
O=C(/C(C1=CC=CO1)=C/C2=CC=C(O2)[N+]([O-])=O)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
プロトコル
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Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Tazima Y, et, al. Mutagenicity of nitrofuran derivatives, including furylfuramide, a food preservative. Mutat Res. 1975;32(1):55-80. [Content Brief]
[2]. Shimada T, et, al. Metabolic deactivation of furylfuramide by cytochrome P450 in human and rat liver microsomes. Carcinogenesis. 1990 Jan;11(1):103-10. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Furylfuramide 関連分類
HY-119669 関連分類
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