GAP-1173149
GAP-1173149 is a Chikungunya Virus polymerase inhibitor targeting the CHIKV nsP4 RNA-dependent RNA polymerase.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1622645-58-2
- 分子式: C14H19N5O3
- 分子量:305.33
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
GAP-1173149 shows EC50 values of 15.6, 18.6, 5.3 and 11.62 μM in U-2 OS cells, Vero cells, CHIKV replicon and normal human dermal fibroblasts[1].
GAP-1173149 shows CC50 values >100 μM in U-2 OS and Vero cells, and >500 μM in normal human dermal fibroblasts[1].
GAP-1173149 (100 μM) exhibits alphavirus-specific activity, inhibiting RNA replication of CHIKV, o’nyong-nyong virus (ONNV), Ross River virus (RRV), Eastern equine encephalitis virus (EEEV) and Barmah Forest virus (BFV), while showing no inhibition on unrelated viruses (HPIV3, RSV, SARS-CoV-2, VSV) or Sindbis virus (SINV)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1622645-58-2
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分子量 305.33
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分子式 C14H19N5O3
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SMILES
O=C(NCC1=NNC2=C1CCCCC2)CN(C(NC3)=O)C3=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
GAP-1173149 関連分類
HY-178334 関連分類
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