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CDYL2 - chromodomain Y like 2 Gene

Also Known as PCCP1

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 124359

About CDYL2

Cytogenetic location: 16q23.2 Genomic coordinates (GRCh38): 16:80,597,907-80,805,037 (from NCBI)

This gene has 7 transcripts (splice variants), 198 orthologues and 13 paralogues. Broad expression in testis (RPKM 6.1), placenta (RPKM 3.9) and 20 other tissues.

Summary

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CDYL2 Products (1)

mRNA	Protein	Name
NM_152342.4	NP_689555.2	chromodomain Y-like protein 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	17577209	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDYL2 Protein Structure

Chromo

ECH_1

0
100
200
300
400
506 a.a.

Protein Preferred Names	Protein Names
chromodomain Y-like protein 2	CDY-like 2

CDYL2 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	CDYL2	Q8N8U2	LMO3	Homo sapiens	Q8TAP4-4	Validated Y2H	32296183
Intra	CDYL2	Q8N8U2	PRMT5	Homo sapiens	O14744	Anti Tag CoIP	23455924
Intra	CDYL2	Q8N8U2	PRMT5	Homo sapiens	O14744	Y2H	23455924
Intra	CDYL2	Q8N8U2	ZBTB9	Homo sapiens	Q96C00	Validated Y2H	32296183
Intra	CDYL2	Q8N8U2	NXF1	Homo sapiens	Q9UBU9	Validated Y2H	32296183
Intra	CDYL2	Q8N8U2	DVL3	Homo sapiens	Q92997	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases	Alias
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS02434	CDYL2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20879	Cdyl2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27396	Cdyl2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Rattus norvegicus	CDYL2	RGD	RGD:1309548
Mus musculus	CDYL2	MGD	MGI:1923046
Macaca mulatta	CDYL2	VGNC	VGNC:71076
Canis familiaris	CDYL2	VGNC	VGNC:53315
Felis catus	CDYL2	VGNC	VGNC:60724
Bos taurus	CDYL2	VGNC	VGNC:27160
Others	CDYL2	NCBI