GRK2 Inhibitor 1
Based on 1 Customer Validation
GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a dual GRK2/β-ARK1 inhibitor that induces dopamine (DA) inhibition reversal (DIR). GRK2 Inhibitor 1 can also block serotonin-induced or neurotensin-induced DIR reversal. Note: DIR refers to the phenomenon in which neurons in addiction-related brain pathways become less sensitive to DA inhibition when exposed to moderate concentrations of DA for a long time.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.06%
- CAS 番号: 24269-96-3
- 分子式: C12H9NO6
- 分子量:263.20
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Dopamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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GRK2 |
化学情報
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CAS 番号 24269-96-3
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性状 Solid
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分子量 263.20
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分子式 C12H9NO6
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Color Yellow to brown
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SMILES
O=C(OC)C1=CC=C(O1)/C=C/C2=CC=C(O2)[N+]([O-])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 41.67 mg/mL (158.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7994 mL | 18.9970 mL | 37.9939 mL | 94.9848 mL |
| 5 mM | 0.7599 mL | 3.7994 mL | 7.5988 mL | 18.9970 mL | |
| 10 mM | 0.3799 mL | 1.8997 mL | 3.7994 mL | 9.4985 mL | |
| 15 mM | 0.2533 mL | 1.2665 mL | 2.5329 mL | 6.3323 mL | |
| 20 mM | 0.1900 mL | 0.9498 mL | 1.8997 mL | 4.7492 mL | |
| 25 mM | 0.1520 mL | 0.7599 mL | 1.5198 mL | 3.7994 mL | |
| 30 mM | 0.1266 mL | 0.6332 mL | 1.2665 mL | 3.1662 mL | |
| 40 mM | 0.0950 mL | 0.4749 mL | 0.9498 mL | 2.3746 mL | |
| 50 mM | 0.0760 mL | 0.3799 mL | 0.7599 mL | 1.8997 mL | |
| 60 mM | 0.0633 mL | 0.3166 mL | 0.6332 mL | 1.5831 mL | |
| 80 mM | 0.0475 mL | 0.2375 mL | 0.4749 mL | 1.1873 mL | |
| 100 mM | 0.0380 mL | 0.1900 mL | 0.3799 mL | 0.9498 mL |
GRK2 Inhibitor 1 関連分類
HY-123538 関連分類
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