HL1
Based on 1 Customer Validation
HL1 is a Schiff base ligand. HL1 exhibits chelation-enhanced fluorescence effect when forming complexes and can be used as a fluorescent probe for metal ions. HL1 can be used for the research of cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.86%
- CAS 番号: 202828-10-2
- 分子式: C11H9ClN4O
- 分子量:248.67
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
HL1 (3.9-500 μM; 24 h) forms Ni2+ and Cu2+ binuclear complexes that show high cytotoxicity against both MDA-MB-231 breast cancer cells and non-cancerous L-6 myoblast cells[1].
HL1 exhibits photoluminescence at a weak and strong excitation wavelength of 415 nm[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 202828-10-2
-
性状 Solid
-
分子量 248.67
-
分子式 C11H9ClN4O
-
Color White to yellow
-
SMILES
ClC1=NN=C(N/N=C/C2=C(O)C=CC=C2)C=C1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 43.75 mg/mL (175.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (270 KB)
-
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0214 mL | 20.1070 mL | 40.2139 mL | 100.5348 mL |
| 5 mM | 0.8043 mL | 4.0214 mL | 8.0428 mL | 20.1070 mL | |
| 10 mM | 0.4021 mL | 2.0107 mL | 4.0214 mL | 10.0535 mL | |
| 15 mM | 0.2681 mL | 1.3405 mL | 2.6809 mL | 6.7023 mL | |
| 20 mM | 0.2011 mL | 1.0053 mL | 2.0107 mL | 5.0267 mL | |
| 25 mM | 0.1609 mL | 0.8043 mL | 1.6086 mL | 4.0214 mL | |
| 30 mM | 0.1340 mL | 0.6702 mL | 1.3405 mL | 3.3512 mL | |
| 40 mM | 0.1005 mL | 0.5027 mL | 1.0053 mL | 2.5134 mL | |
| 50 mM | 0.0804 mL | 0.4021 mL | 0.8043 mL | 2.0107 mL | |
| 60 mM | 0.0670 mL | 0.3351 mL | 0.6702 mL | 1.6756 mL | |
| 80 mM | 0.0503 mL | 0.2513 mL | 0.5027 mL | 1.2567 mL | |
| 100 mM | 0.0402 mL | 0.2011 mL | 0.4021 mL | 1.0053 mL |