HO-PEG11-OH
Based on 1 Customer Validation
HO-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.41%
- CAS 番号: 6809-70-7
- 分子式: C22H46O12
- 分子量:502.59
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Octaethylene glycol -
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Dodecaethylene glycolPROTAC Linkers -
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Nonaethylene glycolPROTAC Linkers -
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Decaethylene glycolPROTAC Linkers -
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Heptaethylene glycolPROTAC Linkers -
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Tetraethylene glycol -
HY-126916
TetrahydropyranyldiethyleneglycolPROTAC Linkers -
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HO-PEG15-OHPROTAC Linkers -
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PEG3-O-CH2COOHPROTAC Linkers -
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THP-PEG1-alcohol
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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PEGs |
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 6809-70-7
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性状 Solid-Liquid Mixture
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分子量 502.59
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分子式 C22H46O12
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Color Colorless to off-white
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SMILES
OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (198.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (264 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9897 mL | 9.9485 mL | 19.8969 mL | 49.7423 mL |
| 5 mM | 0.3979 mL | 1.9897 mL | 3.9794 mL | 9.9485 mL | |
| 10 mM | 0.1990 mL | 0.9948 mL | 1.9897 mL | 4.9742 mL | |
| 15 mM | 0.1326 mL | 0.6632 mL | 1.3265 mL | 3.3162 mL | |
| 20 mM | 0.0995 mL | 0.4974 mL | 0.9948 mL | 2.4871 mL | |
| 25 mM | 0.0796 mL | 0.3979 mL | 0.7959 mL | 1.9897 mL | |
| 30 mM | 0.0663 mL | 0.3316 mL | 0.6632 mL | 1.6581 mL | |
| 40 mM | 0.0497 mL | 0.2487 mL | 0.4974 mL | 1.2436 mL | |
| 50 mM | 0.0398 mL | 0.1990 mL | 0.3979 mL | 0.9948 mL | |
| 60 mM | 0.0332 mL | 0.1658 mL | 0.3316 mL | 0.8290 mL | |
| 80 mM | 0.0249 mL | 0.1244 mL | 0.2487 mL | 0.6218 mL | |
| 100 mM | 0.0199 mL | 0.0995 mL | 0.1990 mL | 0.4974 mL |
HO-PEG11-OH 関連分類
HY-130342 関連分類
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