Human UGT2B15
Human UGT2B15 is a UDP-glucuronosyltransferase. Human UGT2B15 stereoselectively catalyzes the glucuronidation of S-Oxazepam. Human UGT2B15 does not mediate the glucuronidation of R-Oxazepam.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
UGT2B15 |
体外実験
Human UGT2B15 catalyzes the glucuronidation of S-Oxazepam, with an apparent Km value of 35 µM, and its kinetics conform to a non-competitive substrate inhibition model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
SMILES
[Human UGT2B15]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Court MH, et al. Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9. Drug metabolism and disposition: the biological fate of chemicals. 2002 Nov;30(11):1257-65. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)