Human UGT2B17
Human UGT2B17 is a UDP-glucuronosyltransferase. Human UGT2B17 catalyzes the glucuronidation of Testosterone at the 17β-OH position, binds Epitestosteron with comparable affinity, but cannot catalyze its glucuronidation.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
UGT2B17 |
体外実験
Human UGT2B17 (120 min) efficiently catalyzes the glucuronidation of Testosterone at a rate of 508.9 pmol/mg of protein/min, and no glucuronidation activity toward epitestosterone is detected[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
[Human UGT2B17]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Sten T, et al. UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly. Drug Metab Dispos. 2009 Feb;37(2):417-23. [Content Brief]
[2]. Strahm E, et al. Implication of Human UGT2B7, 2B15, and 2B17 in 19-Norandrosterone Metabolism. Frontiers in endocrinology. 2013;4:75. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Human UGT2B17 関連分類
HY-E72115 関連分類
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