Hydroxycotinine-d3
Hydroxycotinine-d3 is the d3-labeled Hydroxycotinine (HY-113239). Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1311275-10-1
- 分子式: C10H9D3N2O2
- 分子量:195.23
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 1311275-10-1
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非標識Cas 34834-67-8
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分子量 195.23
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分子式 C10H9D3N2O2
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SMILES
O[C@@H](C1=O)C[C@](C2=CN=CC=C2)([H])N1C([2H])([2H])[2H]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
溶剤 & 溶解度
体外:
DMSO : 30 mg/mL (153.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
参考文献
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1222 mL | 25.6108 mL | 51.2216 mL | 128.0541 mL |
| 5 mM | 1.0244 mL | 5.1222 mL | 10.2443 mL | 25.6108 mL | |
| 10 mM | 0.5122 mL | 2.5611 mL | 5.1222 mL | 12.8054 mL | |
| 15 mM | 0.3415 mL | 1.7074 mL | 3.4148 mL | 8.5369 mL | |
| 20 mM | 0.2561 mL | 1.2805 mL | 2.5611 mL | 6.4027 mL | |
| 25 mM | 0.2049 mL | 1.0244 mL | 2.0489 mL | 5.1222 mL | |
| 30 mM | 0.1707 mL | 0.8537 mL | 1.7074 mL | 4.2685 mL | |
| 40 mM | 0.1281 mL | 0.6403 mL | 1.2805 mL | 3.2014 mL | |
| 50 mM | 0.1024 mL | 0.5122 mL | 1.0244 mL | 2.5611 mL | |
| 60 mM | 0.0854 mL | 0.4268 mL | 0.8537 mL | 2.1342 mL | |
| 80 mM | 0.0640 mL | 0.3201 mL | 0.6403 mL | 1.6007 mL | |
| 100 mM | 0.0512 mL | 0.2561 mL | 0.5122 mL | 1.2805 mL |