IP6K2-IN-1
Based on 1 Customer Validation
IP6K2-IN-1 is a selective flavonoid-based IP6K2 inhibitor with an IC50 value of 0.55 μM. IP6K2-IN-1 shows higher inhibitory potency against IP6K2 than IP6K1 and IP6K3. IP6K2-IN-1 can be utilised as a hit compound for further structural modifications of IP6K2 inhibitors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.47%
- CAS 番号: 2926679-10-7
- 分子式: C16H10O7
- 分子量:314.25
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
生物活性
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IP6K2 |
IP6K2-IN-1 (Compound 20s) shows IC50 value of 2.87 µM against IP6K1 resulting 5.22-fold IC50 ratio of IP6K1/IP6K2 and IC50 value of 3.56 µM against IP6K3, resulting 6.47-fold IC50 ratio of IP6K3/IP6K2[1].
IP6K2-IN-1 failed to reduce IP7 levels in HCT116 cells, indicating low cell permeability[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2926679-10-7
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性状 Solid
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分子量 314.25
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分子式 C16H10O7
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Color Yellow to brown
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SMILES
OC1=C(O)C=C(C(C(O)=C(C2=CC(C(O)=O)=CC=C2)O3)=O)C3=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)