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製品番号: HY-122724

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IQDMA

Name: IQDMA
Brand: MedChemExpress
SKU: HY-122724
Availability: PreOrder

1 Cited Publications

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

IQDMA is an anti-tumor compound. IQDMA can induce apoptosis in tumor cells, such as K562 cells.

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CAS 番号: 401463-02-3
分子式: C₁₉H₂₀N₄
分子量:304.39

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

IQDMA 構造式

CAS 番号: 401463-02-3

容量

価格（税別）

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数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IQDMA is an anti-tumor compound. IQDMA can induce apoptosis in tumor cells, such as K562 cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.83 μM Compound: 12a	Antiproliferative activity against human A549 cells by MTT assay Antiproliferative activity against human A549 cells by MTT assay	[PMID: 20171108]
Detroit 551	IC₅₀	2.21 μM Compound: 12a	Antiproliferative activity against human Detroit 551 cells by MTT assay Antiproliferative activity against human Detroit 551 cells by MTT assay	[PMID: 20171108]
HeLa	IC₅₀	0.61 μM Compound: 12a	Antiproliferative activity against human HeLa cells by MTT assay Antiproliferative activity against human HeLa cells by MTT assay	[PMID: 20171108]
L6	IC₅₀	626.8 nM Compound: 14k	Cytotoxicity against rat L6 cells assessed as cell growth inhibition Cytotoxicity against rat L6 cells assessed as cell growth inhibition	[PMID: 34710743]
PC-3	IC₅₀	5.79 μM Compound: 12a	Antiproliferative activity against human PC3 cells by MTT assay Antiproliferative activity against human PC3 cells by MTT assay	[PMID: 20171108]

化学情報

CAS 番号 401463-02-3
分子量 304.39
分子式 C₁₉H₂₀N₄
SMILES

CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=C(N3)C=CC=C4
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Sci Adv

JAK/STAT signaling pathway affects CCR5 expression in human CD4+ T cells. [Abstract]

2024 Mar 22;10(12):eadl0368. PMID: 38507500

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (274 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Lin, et al. "Induction of G2/M phase arrest and apoptosis by a novel indoloquinoline derivative, IQDMA, in K562 cells." Drug development research 67.9 (2006): 743-751.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

IQDMA

1 Cited Publications

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生物活性
- 製品説明
化学情報
Publications (1)
純度とドキュメンテーション
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IQDMA

MedChemExpress（MCE）の使用を引用している文献 IQDMA

生物活性

化学情報

Publications (1)

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

IQDMA 関連分類

HY-122724 関連分類

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