IR-806
Based on 1 Customer Validation
IR-806 is a near-infrared cyanine liquid crystal dye. IR-806 can be used as a molecular antenna to synthesized nanoprobes (NPs). IR-806 can be used for in vivo imaging studies.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.84%
- CAS 番号: 757960-10-4
- 分子式: C37H44ClN2NaO6S2
- 分子量:735.33
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
IR-806 (0.1 mg) and folic acid (0.02 mg) were activated with EDC/NHS (1×10−4 mol) in DMSO (10 mL) solution. After 30 mins, the PL-PEG-NH2 coated UCN solution (containing UCNs 5 mg) was added and stirred at room temperature for 4 hrs. The reaction product was purified by centrifugation at 10,000 rpm for 5 mins and suspended in 5 mL of DMSO, obtained upconversion nanocrystals (UCNs) for the preparation of nanoprobes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 757960-10-4
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性状 Solid
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分子量 735.33
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分子式 C37H44ClN2NaO6S2
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Color Green to dark green
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SMILES
CC(C)(/C1=C/C=C2C(Cl)=C(CC/2)/C=C/C3=[N+](C4=C(C3(C)C)C=CC=C4)CCCCS(=O)(O[Na])=O)C5=C(C=CC=C5)N1CCCCS(=O)([O-])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (135.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Zhang YF, et al. Multiple hybridized resonances of IR-806 chromonic molecules strongly coupled to Au nanorods. Nanoscale. 2015 May 14;7(18):8503-9. [Content Brief]
[2]. Wei Y, et al. Molecular Antenna-Sensitized Upconversion Nanoparticle for Temperature Monitored Precision Photothermal Therapy. Int J Nanomedicine. 2020 Mar 2;15:1409-1420. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3599 mL | 6.7997 mL | 13.5993 mL | 33.9983 mL |
| 5 mM | 0.2720 mL | 1.3599 mL | 2.7199 mL | 6.7997 mL | |
| 10 mM | 0.1360 mL | 0.6800 mL | 1.3599 mL | 3.3998 mL | |
| 15 mM | 0.0907 mL | 0.4533 mL | 0.9066 mL | 2.2666 mL | |
| 20 mM | 0.0680 mL | 0.3400 mL | 0.6800 mL | 1.6999 mL | |
| 25 mM | 0.0544 mL | 0.2720 mL | 0.5440 mL | 1.3599 mL | |
| 30 mM | 0.0453 mL | 0.2267 mL | 0.4533 mL | 1.1333 mL | |
| 40 mM | 0.0340 mL | 0.1700 mL | 0.3400 mL | 0.8500 mL | |
| 50 mM | 0.0272 mL | 0.1360 mL | 0.2720 mL | 0.6800 mL | |
| 60 mM | 0.0227 mL | 0.1133 mL | 0.2267 mL | 0.5666 mL | |
| 80 mM | 0.0170 mL | 0.0850 mL | 0.1700 mL | 0.4250 mL | |
| 100 mM | 0.0136 mL | 0.0680 mL | 0.1360 mL | 0.3400 mL |