JMV 170
JMV 170, a CCK derivative, is a selective CCK-B agonist. JMV 170 binds to the CCK-B receptor with a 10-fold higher affinity than to the CCK-A receptor. JMV 170 shows contractile effects on pig smooth muscle cells with an EC50 of 9 pmol/L.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 117829-60-4
- 分子式: C51H68N8O14S
- 分子量:1049.21
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
化学情報
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CAS 番号 117829-60-4
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分子量 1049.21
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分子式 C51H68N8O14S
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SMILES
C([C@@H](C(N[C@H](C(N[C@H](C(NCCC1=CC=CC=C1)=O)CC(O)=O)=O)CCCC)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(OS(=O)(=O)O)C=C2)NC(OC(C)(C)C)=O)=O)CCCC)=O)=O)C=3C=4C(NC3)=CC=CC4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Gue M, et al. Neuropeptide Y and sigma ligand (JO 1784) suppress stress-induced colonic motor disturbances in rats through sigma and cholecystokinin receptors. J Pharmacol Exp Ther. 1992 Jun;261(3):850-5. [Content Brief]
[2]. Botella A, et al. Cholecystokinin and gastrin induce cell contraction in pig ileum by interacting with different receptor subtypes. Gastroenterology. 1992 Mar;102(3):779-86. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)