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製品番号: HY-N5126

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Juncusol

Name: Juncusol
Brand: MedChemExpress
SKU: HY-N5126
Price: 220.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Juncusol, a phenanthrenoid found in Juncus setchuenensis, possesses anxiolytic effect. Juncusol is associated with metabolic changes in cortical serotonin/dopamine levels in Mice.

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CAS 番号: 62023-90-9
分子式: C₁₈H₁₈O₂
分子量:266.33

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Juncusol 構造式

CAS 番号: 62023-90-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Juncusol, a phenanthrenoid found in Juncus setchuenensis, possesses anxiolytic effect. Juncusol is associated with metabolic changes in cortical serotonin/dopamine levels in Mice^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
B16	IC₅₀	12.5 μg/mL Compound: 1a	In vitro cytotoxic activity against B-16 mouse melanoma (B-16) In vitro cytotoxic activity against B-16 mouse melanoma (B-16)	[PMID: 4045930]
HEK293	IC₅₀	6.5 μM Compound: 8	Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay	[PMID: 30892891]
L1210	IC₅₀	13.8 μg/mL Compound: 1a	In vitro cytotoxic activity against L-1210 mouse lymphocytic leukemia cell culture (ATCC CCL-219) In vitro cytotoxic activity against L-1210 mouse lymphocytic leukemia cell culture (ATCC CCL-219)	[PMID: 4045930]
RAW264.7	IC₅₀	3.1 μM Compound: Juncusol	Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay	[PMID: 29280630]

化学情報

CAS 番号 62023-90-9
分子量 266.33
分子式 C₁₈H₁₈O₂
SMILES

OC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C(C)=C3C=C
Structure Classification
- Phenols
- Polyphenols
- Others
Initial Source
- Plants
- other families
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Lu Sun, et al. Anxiolytic effect of a novel 9,10-dihydrophenanthrene, juncuenin H, is associated with metabolic changes in cortical serotonin/dopamine levels in mice. Fitoterapia. 2019 Apr;134:165-171. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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