JX237
Based on 1 Customer Validation
JX237 is an inhibitor of the epithelial neutral amino acid transporter B0AT1 (SLC6A19) with an IC50 value of 31 nM. SLC6A19 is the main transporter for the absorption of neutral amino acids in the intestines and their reabsorption in the kidneys. By inhibiting B0AT1, JX237 can be used for the study of disorders of amino acid metabolism.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.84%
- CAS 番号: 1021125-90-5
- 分子式: C11H15BrN2O
- 分子量:271.15
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
JX237 inhibits B0AT1 (SLC6A19) with an IC50 of 280 nM in radioactive L-leucine uptake assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1021125-90-5
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性状 Solid
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分子量 271.15
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分子式 C11H15BrN2O
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Color Yellow to brown
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SMILES
BrC1=C(C)C=C(NCC(NCC)=O)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 250 mg/mL (922.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6880 mL | 18.4400 mL | 36.8800 mL | 92.1999 mL |
| 5 mM | 0.7376 mL | 3.6880 mL | 7.3760 mL | 18.4400 mL | |
| 10 mM | 0.3688 mL | 1.8440 mL | 3.6880 mL | 9.2200 mL | |
| 15 mM | 0.2459 mL | 1.2293 mL | 2.4587 mL | 6.1467 mL | |
| 20 mM | 0.1844 mL | 0.9220 mL | 1.8440 mL | 4.6100 mL | |
| 25 mM | 0.1475 mL | 0.7376 mL | 1.4752 mL | 3.6880 mL | |
| 30 mM | 0.1229 mL | 0.6147 mL | 1.2293 mL | 3.0733 mL | |
| 40 mM | 0.0922 mL | 0.4610 mL | 0.9220 mL | 2.3050 mL | |
| 50 mM | 0.0738 mL | 0.3688 mL | 0.7376 mL | 1.8440 mL | |
| 60 mM | 0.0615 mL | 0.3073 mL | 0.6147 mL | 1.5367 mL | |
| 80 mM | 0.0461 mL | 0.2305 mL | 0.4610 mL | 1.1525 mL | |
| 100 mM | 0.0369 mL | 0.1844 mL | 0.3688 mL | 0.9220 mL |
JX237 関連分類
HY-162864 関連分類
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