K-TMZ
K-TMZ is a derivative of methyl ketone, which exhibits antitumor efficacy against O6 -methylguanine DNA methyltransferase (MGMT) deficient cell. K-TMZ can be used for research of glioblastoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2269482-26-8
- 分子式: C7H7N5O2
- 分子量:193.16
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-119696
MTICTemozolomide Metabolite -
HY-17364
TemozolomideDNA Alkylator -
HY-13593
ChlorambucilDNA Alkylator -
HY-13747
SemustineAntitumor Alkylating Agent -
HY-119696R
MTIC (Standard)Temozolomide Metabolite -
HY-13543
TretazicarDNA Cross-linking Agent -
HY-13593R
Chlorambucil (Standard)DNA Alkylator -
HY-17364R
Temozolomide (Standard)DNA Alkylator -
HY-13543R
Tretazicar (Standard)DNA Cross-linking Agent -
HY-153154
COMC-6Anticancer Agent
生物活性
製品説明
化学情報
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CAS 番号 2269482-26-8
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分子量 193.16
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分子式 C7H7N5O2
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SMILES
O=C(N(C)N=N1)N2C1=C(C(C)=O)N=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Patient-Derived Xenograft (PDX)
Patient-derived xenograft (PDX) models are generated by engrafting primary human tumor tissue directly into immunodeficient mice, allowing in vivo propagation of patient tumor biology without initial in vitro adaptation. These models are used to preserve key histopathological and molecular characteristics of the original tumor and enable assessment of tumor growth dynamics and therapeutic response in a living organism. The biological readout is tumor engraftment and subsequent growth in the murine host, which reflects the ability of human tumor cells to survive, vascularize, and expand in an immunocompromised microenvironment.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
K-TMZ 関連分類
HY-115690 関連分類
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