KR-12 (human)
Based on 1 Customer Validation
KR-12 (human) is an active segment of LL-37 (HY-P4744). KR-12 (human) exhibits antimicrobial activity against gram-negative bacteria. KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM. KR-12 human can be used for the research of infection, such as E. coli infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.91%
- CAS 番号: 1218951-51-9
- 分子式: C71H127N25O15
- 分子量:1570.93
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM[1].
KR-12 (human) is inactive against S. aureus UAMS-1 and USA300 with MIC values >264 μM[1].
KR-12 (human) (40 μM) shows Little or no leakage from E. coli cytoplasmic membranes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1218951-51-9
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性状 Solid
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分子量 1570.93
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分子式 C71H127N25O15
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Color White to off-white
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配列
Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2
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シーケンスの短縮
KRIVQRIKDFLR-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : ≥ 100 mg/mL (63.66 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6366 mL | 3.1828 mL | 6.3657 mL | 15.9141 mL |
| 5 mM | 0.1273 mL | 0.6366 mL | 1.2731 mL | 3.1828 mL | |
| 10 mM | 0.0637 mL | 0.3183 mL | 0.6366 mL | 1.5914 mL | |
| 15 mM | 0.0424 mL | 0.2122 mL | 0.4244 mL | 1.0609 mL | |
| 20 mM | 0.0318 mL | 0.1591 mL | 0.3183 mL | 0.7957 mL | |
| 25 mM | 0.0255 mL | 0.1273 mL | 0.2546 mL | 0.6366 mL | |
| 30 mM | 0.0212 mL | 0.1061 mL | 0.2122 mL | 0.5305 mL | |
| 40 mM | 0.0159 mL | 0.0796 mL | 0.1591 mL | 0.3979 mL | |
| 50 mM | 0.0127 mL | 0.0637 mL | 0.1273 mL | 0.3183 mL | |
| 60 mM | 0.0106 mL | 0.0530 mL | 0.1061 mL | 0.2652 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
KR-12 (human) 関連分類
HY-P10257 関連分類
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