ロイコマラカイトグリーン
Based on 1 publication(s) in Google Scholar
Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.72%
- CAS 番号: 129-73-7
- 分子式: C23H26N2
- 分子量:330.47
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Leucomalachite green
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生物活性
Leucomalachite green (30-610 μM; 24 h) does not significantly inhibit cell viability (neutral red uptake assay, total protein content assay) and proliferation ability (colony formation assay) in HEp-2 human laryngeal cancer cell line, showing low cytotoxicity[2].
Leucomalachite green (25-100 μM; 24 h) does not show significant cytotoxicity in Caco-2 human colon cancer cell line experiments, as detected by MTT assay, LDH leakage assay and neutral red uptake assay[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 129-73-7
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性状 Solid
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分子量 330.47
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分子式 C23H26N2
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Color White to off-white
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SMILES
CN(C)C1=CC=C(C(C2=CC=C(N(C)C)C=C2)C3=CC=CC=C3)C=C1
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別名
Leucomalachite green
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Pharmaceuticals (Basel)
Identification of SARS-CoV-2 Main Protease Inhibitors Using Chemical Similarity Analysis Combined with Machine Learning. [Abstract]2024 Feb 12;17(2):240. PMID: 38399455
溶剤 & 溶解度
DMSO : 100 mg/mL (302.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Portuguese - PT (418 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Ya-hui Li, et al. Development of a group selective molecularly imprinted polymers based solid phase extraction of malachite green from fish water and fish feed samples. Anal Chim Acta. 2008 Aug 29;624(2):317-25. [Content Brief]
[2]. Stammati A, et al. Effects of malachite green (MG) and its major metabolite, leucomalachite green (LMG), in two human cell lines. Toxicol In Vitro. 2005 Oct;19(7):853-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0260 mL | 15.1300 mL | 30.2599 mL | 75.6498 mL |
| 5 mM | 0.6052 mL | 3.0260 mL | 6.0520 mL | 15.1300 mL | |
| 10 mM | 0.3026 mL | 1.5130 mL | 3.0260 mL | 7.5650 mL | |
| 15 mM | 0.2017 mL | 1.0087 mL | 2.0173 mL | 5.0433 mL | |
| 20 mM | 0.1513 mL | 0.7565 mL | 1.5130 mL | 3.7825 mL | |
| 25 mM | 0.1210 mL | 0.6052 mL | 1.2104 mL | 3.0260 mL | |
| 30 mM | 0.1009 mL | 0.5043 mL | 1.0087 mL | 2.5217 mL | |
| 40 mM | 0.0756 mL | 0.3782 mL | 0.7565 mL | 1.8912 mL | |
| 50 mM | 0.0605 mL | 0.3026 mL | 0.6052 mL | 1.5130 mL | |
| 60 mM | 0.0504 mL | 0.2522 mL | 0.5043 mL | 1.2608 mL | |
| 80 mM | 0.0378 mL | 0.1891 mL | 0.3782 mL | 0.9456 mL | |
| 100 mM | 0.0303 mL | 0.1513 mL | 0.3026 mL | 0.7565 mL |
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