LI-3948
Based on 1 Customer Validation
IP6K-IN-2 (compound 29c) is an orally bioavailable and blood-brain barrier permeable IP6K inhibitor (IC50: 15.8 nM) that can be used in the study of central nervous system diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.85%
- CAS 番号: 3024591-38-3
- 分子式: C19H16Cl2FN3O3
- 分子量:424.25
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
IC50 & Target
IC50: 15.8 nM (IP6K)[1]
化学情報
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CAS 番号 3024591-38-3
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性状 Solid
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分子量 424.25
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分子式 C19H16Cl2FN3O3
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Color White to off-white
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SMILES
FC1=C(C(N)=O)C=CC(N2)=C1[C@]3(CC[C@H](OC4=NC=C(Cl)C=C4Cl)CC3)C2=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (235.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3571 mL | 11.7855 mL | 23.5710 mL | 58.9275 mL |
| 5 mM | 0.4714 mL | 2.3571 mL | 4.7142 mL | 11.7855 mL | |
| 10 mM | 0.2357 mL | 1.1786 mL | 2.3571 mL | 5.8928 mL | |
| 15 mM | 0.1571 mL | 0.7857 mL | 1.5714 mL | 3.9285 mL | |
| 20 mM | 0.1179 mL | 0.5893 mL | 1.1786 mL | 2.9464 mL | |
| 25 mM | 0.0943 mL | 0.4714 mL | 0.9428 mL | 2.3571 mL | |
| 30 mM | 0.0786 mL | 0.3929 mL | 0.7857 mL | 1.9643 mL | |
| 40 mM | 0.0589 mL | 0.2946 mL | 0.5893 mL | 1.4732 mL | |
| 50 mM | 0.0471 mL | 0.2357 mL | 0.4714 mL | 1.1786 mL | |
| 60 mM | 0.0393 mL | 0.1964 mL | 0.3929 mL | 0.9821 mL | |
| 80 mM | 0.0295 mL | 0.1473 mL | 0.2946 mL | 0.7366 mL | |
| 100 mM | 0.0236 mL | 0.1179 mL | 0.2357 mL | 0.5893 mL |