LIMK-IN-2
LIMK-IN-2 (Compound 52) is an LIMK inhibitor. LIMK-IN-2 can suppress the cell migration of osteosarcoma and cervical cancer cells, demonstrating potential anti-angiogenic activity.
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- CAS 番号: 2747216-27-7
- 分子式: C28H27N5O2
- 分子量:465.55
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Fibroblast | EC50 |
>25 μM
Compound: 52
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Cytotoxicity against human skin fibroblast cells assessed as inhibition of cell growth measured after 48 hrs by Hoechst 33342 staining based analysis
Cytotoxicity against human skin fibroblast cells assessed as inhibition of cell growth measured after 48 hrs by Hoechst 33342 staining based analysis
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[PMID: 38669909] |
| HeLa | EC50 |
26 μM
Compound: 52
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Cytotoxicity against human HeLa cells assessed as induction of cell death measured after 48 hrs by celltiter glo luminescent cell viability assay
Cytotoxicity against human HeLa cells assessed as induction of cell death measured after 48 hrs by celltiter glo luminescent cell viability assay
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[PMID: 38669909] |
| KHOS/NP | IC50 |
6.2 μM
Compound: 52
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Cytotoxicity against human KHOS/NP cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based analysis
Cytotoxicity against human KHOS/NP cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based analysis
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[PMID: 38669909] |
| U2OS | IC50 |
9.5 μM
Compound: 52
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Cytotoxicity against human U2OS cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter Aqueous One Solution Cell Proliferation Assay
Cytotoxicity against human U2OS cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter Aqueous One Solution Cell Proliferation Assay
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[PMID: 38669909] |
化学情報
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CAS 番号 2747216-27-7
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分子量 465.55
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分子式 C28H27N5O2
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SMILES
COC1=CC=CC(C2=CC(NC(N3CCC(C4=C5C(NC=C5C6CC6)=NC=N4)=CC3)=O)=CC=C2)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
LIMK-IN-2 関連分類
HY-161417 関連分類
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