Lipstatin
Based on 1 Customer Validation
Lipstatin is a pancreatic lipase inhibitor (IC50=0.14 μM), whose structure is closely related to the known inhibitor, Esterastin. Lipstatin inhibits the absorption of triglycerides without affecting the absorption of oleic acid. Lipstatin has no inhibitory effects on other pancreatic enzymes, such as phospholipase A2 and trypsin (<200 μM).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 80.0%
- CAS 番号: 96829-59-3
- 分子式: C29H49NO5
- 分子量:491.70
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保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
化学情報
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CAS 番号 96829-59-3
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性状 Liquid (Density: 0.993±0.06 g/cm3)
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分子量 491.70
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分子式 C29H49NO5
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Color Colorless to light yellow
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SMILES
CC(C)C[C@@H](C(O[C@H](C[C@@H]([C@@H]1CCCCCC)OC1=O)C/C=C\C/C=C\CCCCC)=O)NC=O
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Structure Classification
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Initial Source
Streptomyces
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 200 mg/mL (406.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Hochuli E, et al. Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. II. Chemistry and structure elucidation. J Antibiot (Tokyo). 1987 Aug;40(8):1086-91. [Content Brief]
[2]. Weibel EK, et al. Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity. J Antibiot (Tokyo). 1987 Aug;40(8):1081-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0338 mL | 10.1688 mL | 20.3376 mL | 50.8440 mL |
| 5 mM | 0.4068 mL | 2.0338 mL | 4.0675 mL | 10.1688 mL | |
| 10 mM | 0.2034 mL | 1.0169 mL | 2.0338 mL | 5.0844 mL | |
| 15 mM | 0.1356 mL | 0.6779 mL | 1.3558 mL | 3.3896 mL | |
| 20 mM | 0.1017 mL | 0.5084 mL | 1.0169 mL | 2.5422 mL | |
| 25 mM | 0.0814 mL | 0.4068 mL | 0.8135 mL | 2.0338 mL | |
| 30 mM | 0.0678 mL | 0.3390 mL | 0.6779 mL | 1.6948 mL | |
| 40 mM | 0.0508 mL | 0.2542 mL | 0.5084 mL | 1.2711 mL | |
| 50 mM | 0.0407 mL | 0.2034 mL | 0.4068 mL | 1.0169 mL | |
| 60 mM | 0.0339 mL | 0.1695 mL | 0.3390 mL | 0.8474 mL | |
| 80 mM | 0.0254 mL | 0.1271 mL | 0.2542 mL | 0.6356 mL | |
| 100 mM | 0.0203 mL | 0.1017 mL | 0.2034 mL | 0.5084 mL |
Lipstatin 関連分類
HY-N2330 関連分類
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