Lonazolac
Based on 1 Customer Validation
Lonazolac is a non-steroidal antirheumatic agent. Anti-inflammatory effects .
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.59%
- CAS 番号: 53808-88-1
- 分子式: C17H13ClN2O2
- 分子量:312.75
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保管条件:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
生物活性
製品説明
化学情報
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CAS 番号 53808-88-1
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性状 Solid
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分子量 312.75
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分子式 C17H13ClN2O2
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Color Light yellow to yellow
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SMILES
O=C(O)CC1=CN(C2=CC=CC=C2)N=C1C3=CC=C(Cl)C=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (399.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Trnavský K, et al. [Lonazolac - a new non-steroidal antirheumatic agent. Report of a double-blind crossover clinical study]. Fysiatr Revmatol Vestn. 1983;61(3):147-152. [Content Brief]
[2]. Harras MF, et al. Discovery of new non-acidic lonazolac analogues with COX-2 selectivity as potent anti-inflammatory agents. Medchemcomm. 2019;10(10):1775-1788. Published 2019 Jul 22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1974 mL | 15.9872 mL | 31.9744 mL | 79.9361 mL |
| 5 mM | 0.6395 mL | 3.1974 mL | 6.3949 mL | 15.9872 mL | |
| 10 mM | 0.3197 mL | 1.5987 mL | 3.1974 mL | 7.9936 mL | |
| 15 mM | 0.2132 mL | 1.0658 mL | 2.1316 mL | 5.3291 mL | |
| 20 mM | 0.1599 mL | 0.7994 mL | 1.5987 mL | 3.9968 mL | |
| 25 mM | 0.1279 mL | 0.6395 mL | 1.2790 mL | 3.1974 mL | |
| 30 mM | 0.1066 mL | 0.5329 mL | 1.0658 mL | 2.6645 mL | |
| 40 mM | 0.0799 mL | 0.3997 mL | 0.7994 mL | 1.9984 mL | |
| 50 mM | 0.0639 mL | 0.3197 mL | 0.6395 mL | 1.5987 mL | |
| 60 mM | 0.0533 mL | 0.2665 mL | 0.5329 mL | 1.3323 mL | |
| 80 mM | 0.0400 mL | 0.1998 mL | 0.3997 mL | 0.9992 mL | |
| 100 mM | 0.0320 mL | 0.1599 mL | 0.3197 mL | 0.7994 mL |