m-PEG11-OH
Based on 1 Customer Validation
m-PEG11-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.83%
- CAS 番号: 2168540-65-4
- 分子式: C23H48O12
- 分子量:516.62
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
[1]|
PEGs |
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2168540-65-4
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性状 Liquid (Density: 1.086 g/cm3)
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分子量 516.62
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分子式 C23H48O12
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Color Colorless to light yellow
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SMILES
OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (193.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9357 mL | 9.6783 mL | 19.3566 mL | 48.3915 mL |
| 5 mM | 0.3871 mL | 1.9357 mL | 3.8713 mL | 9.6783 mL | |
| 10 mM | 0.1936 mL | 0.9678 mL | 1.9357 mL | 4.8391 mL | |
| 15 mM | 0.1290 mL | 0.6452 mL | 1.2904 mL | 3.2261 mL | |
| 20 mM | 0.0968 mL | 0.4839 mL | 0.9678 mL | 2.4196 mL | |
| 25 mM | 0.0774 mL | 0.3871 mL | 0.7743 mL | 1.9357 mL | |
| 30 mM | 0.0645 mL | 0.3226 mL | 0.6452 mL | 1.6130 mL | |
| 40 mM | 0.0484 mL | 0.2420 mL | 0.4839 mL | 1.2098 mL | |
| 50 mM | 0.0387 mL | 0.1936 mL | 0.3871 mL | 0.9678 mL | |
| 60 mM | 0.0323 mL | 0.1613 mL | 0.3226 mL | 0.8065 mL | |
| 80 mM | 0.0242 mL | 0.1210 mL | 0.2420 mL | 0.6049 mL | |
| 100 mM | 0.0194 mL | 0.0968 mL | 0.1936 mL | 0.4839 mL |
m-PEG11-OH 関連分類
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