Machaeric acid
Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells.
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- CAS 番号: 511-81-9
- 分子式: C30H46O4
- 分子量:470.68
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Machaeric acid (compound 1) (200 μM; 48 h) does not exhibit significant cytotoxicity against H4IIE rat hepatoma cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:H4IIE rat hepatoma cells
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Concentration:200 μM
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Incubation Time:48 h
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Result:Was not significantly cytotoxic to H4IIE rat hepatoma cells at 200 μM.
化学情報
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CAS 番号 511-81-9
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分子量 470.68
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分子式 C30H46O4
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SMILES
OC([C@]12[C@](CC(C)(C(C2)=O)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Huo Y, et al. Antinociceptive activity and chemical composition of constituents from Caragana microphylla seeds. Phytomedicine. 2007;14(2-3):143-146. [Content Brief]
[2]. Tchoukoua A, et al. Triterpene saponins from the roots of Acacia senegal (L.) Willd. Fitoterapia. 2021;151:104859. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)