Mal-β-CD
Based on 2 publication(s) in Google Scholar
Mal-β-CD is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.91%
- CAS 番号: 104723-60-6
- 分子式: C54H90O45
- 分子量:1459.27
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 Mal-β-CD
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生物活性
Mal-β-CD removes cellular cholesterol forming inclusion complexes, while Mal-β-CD-induced lack of cellular cholesterol is replenished by the addition of cholesterol/Mal-β-CD inclusion complex (CLM) without cytotoxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 104723-60-6
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性状 Solid
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分子量 1459.27
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分子式 C54H90O45
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Color White to off-white
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SMILES
O[C@@H]1[C@@H](CO)O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](OC[C@H]3O[C@H](O[C@@H]4[C@@H](CO)O[C@H](O[C@@H]5[C@@H](CO)O[C@H](O6)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@@H]3O[C@H]7O[C@H](CO)[C@@H](O[C@@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]9[C@H](O)[C@@H](O)[C@H](OC%10[C@H](O)[C@@H](O)[C@H]6[C@@H](CO)O%10)[C@@H](CO)O9)[C@@H](CO)O8)[C@H](O)[C@H]7O)O[C@@H]2CO)[C@H](O)[C@H]1O
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別名
6-O-alpha-D-Maltosyl-beta-cyclodextrin
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Biochem Biophys Res Commun
Avapritinib efficacy in primary hepatic neuroendocrine carcinoma with elevated PDGFRA expression: Insights from a PDX model study. [Abstract]2024 Aug 6:736:150504. PMID: 39121673 -
Biosci Biotechnol Biochem
Solubilization and stabilization of lipoic acid trisulfide by creation of various β-cyclodextrin clathrates. [Abstract]2024 May 22;88(6):601-607. PMID: 38569654
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (68.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 60.5 mg/mL (41.46 mM)
* "≥" means soluble, but saturation unknown.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
純度とドキュメンテーション
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データシート (286 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 0.6853 mL | 3.4264 mL | 6.8527 mL | 17.1319 mL |
| 5 mM | 0.1371 mL | 0.6853 mL | 1.3705 mL | 3.4264 mL | |
| 10 mM | 0.0685 mL | 0.3426 mL | 0.6853 mL | 1.7132 mL | |
| 15 mM | 0.0457 mL | 0.2284 mL | 0.4568 mL | 1.1421 mL | |
| 20 mM | 0.0343 mL | 0.1713 mL | 0.3426 mL | 0.8566 mL | |
| 25 mM | 0.0274 mL | 0.1371 mL | 0.2741 mL | 0.6853 mL | |
| 30 mM | 0.0228 mL | 0.1142 mL | 0.2284 mL | 0.5711 mL | |
| 40 mM | 0.0171 mL | 0.0857 mL | 0.1713 mL | 0.4283 mL | |
| DMSO | 50 mM | 0.0137 mL | 0.0685 mL | 0.1371 mL | 0.3426 mL |
| 60 mM | 0.0114 mL | 0.0571 mL | 0.1142 mL | 0.2855 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.